One of Massachusetts’ top cannabis officials has stepped down from her position, the Attorney General’s Office said Monday evening.

Ava Callendar Concepcion, who was appointed to the Cannabis Control Commission in January 2021 by then-Attorney General Maura Healey, resigned as the end of her five-year term approached, according to Attorney General Andrea Campbell.

“Commissioner Concepcion has dedicated her career to social justice and brought a wealth of experience in public safety, equity and opportunity to her nearly five years on the Cannabis Control Commission,”Campbell said in a statement. “I am grateful to Commissioner Concepcion for her public service and wish her and her family the very best as she embarks on the next chapter.”

Concepcion had stepped away from commission duties last year and had not taken part in some meetings this year. The Boston Globe reported in August 2024 that the commissioner was planning to take medical leave “for at least the next month.”

Her resignation comes about six months after her former colleague, Commissioner Nurys Camargo, also stepped down from the board.

Camargo’s seat was filled earlier this month by Carrie Benedon, the attorney general’s director of the Division of Open Government since 2018.

The resignation also came about two months after a judge reinstated Commission Chair Shannon O’Brien, whom Treasurer Deborah Goldberg had suspended and attempted to fire two years prior over claims she had mistreated staff.

The judge found Goldberg’s claims that O’Brien committed “gross misconduct” to be insufficient for removing O’Brien from the job and not backed by the evidence.

In O’Brien’s extended absence, Concepcion served for a period as acting chair.

Before serving on the commission, Concepcion was director of governmental affairs and external partnerships for the Suffolk County District Attorney’s Office, where she advised the Boston area’s top prosecutor on legislation and policy.

By law, Concepcion’s seat on the five-member commission must be appointed by the attorney general, who did not indicate Monday who she planned to offer the job.

The seat Benedon took over from Camargo is jointly appointed by the state’s governor, attorney general and treasurer.

However, state lawmakers have proposed changing the structure of the commission, which was plagued in recent years by accusations of internal dysfunction and mismanagement of the pot industry.

A bill passed by the state House of Representatives in June would downsize the board to three members — one full-time commission chair and two part-time commissioners — and place all under the authority of the governor.

The Senate last week advanced its version of the bill, with a slightly different adjustment to the commission structure: The chairperson and another commissioner would be appointed by the governor, and a third commissioner would be appointed by the attorney general, according to State House News Service.

• Read more: How would changes to the Mass. cannabis law affect you and your local pot shop?

Industry advocates have said shrinking the commission could generate quicker action from a board accused of being frustratingly slow to respond to developments in the rapidly evolving industry or roll out new regulations.

However, it could also centralize more power under a single politician, exposing the industry to more influence if the state elects a governor who wants to see cannabis access restricted.