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The number 21 holds a lot of symbolism in Bitcoin circles, as there will only ever be 21 million coins. MicroStrategy (NASDAQ:MSTR) Chair Michael Saylor has leaned into this symbolism to offer one of his most ambitious Bitcoin price predictions yet.

Saylor said on Saturday at BTC Prague 2025 that Bitcoin was heading towards $21 million by 2046.

“Twenty one million coins at a $21 million price in 21 years,” he said. “And people ask, how’s the network going to grow? It’s going to be growing at 21% in 21 years. The volatility is going to be 21. The only number you need to remember is the number 21.”

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Saylor’s most recent prediction represents a significant bump over his previous long-term Bitcoin price prediction. At the Bitcoin 2024 conference, he outlined a “base case” scenario that would see Bitcoin hit $13 million by 2045, growing at 29% annually.

On Saturday, Saylor said a lot has changed since last July. He pointed out that since then, the White House, over 130 corporations, Wall Street and regulators have embraced Bitcoin.

“Stuff that’s happened in the past 11 months has been extraordinary,” he said.

Saylor’s confidence in Bitcoin’s growth potential comes as, despite these positive developments, the asset only accounts for 0.2% of global wealth.

“Bitcoin is winning, and yet 99.8% of the capital in the world still pretends and acts like it isn’t,” he said. “You know something the rest of the world has not yet acknowledged, and yet it couldn’t be clearer to all of us in this room, there’s a monetary revolution afoot, a revolution in economic thinking. It’s spreading everywhere in the world. It’s fueled by the digital transformation of the capital markets that you see manifested in all of these companies and all of these securities.”

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Saylor urged Bitcoin believers to employ every tool at their disposal, from dollar cost averaging to leverage, to take advantage of the potential opportunity before his $21 million price prediction is fulfilled.

He said that the asset’s path to $21 million would not be without turbulence but maintained that the brave would be rewarded.