Prime Big Deal Days are here, and this is the perfect opportunity to shop some of the best deals of the year. During the 48-hour sale, which is exclusive to Prime members, you can find major discounts on bestsellers across beauty, tech, home essentials and more.

As an editorial intern for NBC Select, I’ve spent weeks reviewing thousands of offers to find the best October Prime Day deals — every item I recommend below is what readers have shopped the most so far during the sale, highly rated, at least 20% off and at its lowest price in at least three months. I’ll frequently update this list throughout Prime Big Deal Days so you won’t miss a single bestselling deal.

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October Prime Day 2025 bestsellers

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Why trust NBC Select?

I’m an editorial and production intern for NBC Select covering deals and sales for Amazon Prime Day. For this article, I compiled the most noteworthy bestsellers during Prime Big Deals Days.

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